Important words and concepts from Stryer Biochemistry, Fourth Edition (5/31/01):

by Stephen T. Abedon (abedon.1@osu.edu) for Biochemistry 511 at the Ohio State University

 

 

Course-external links are in brackets

Click here to access text's website

Table of Contents are found below

 

Text Table of Contents with Links to Text Website and Other Notes

(Key: Covered, Partially Covered, Not Covered, Unsure)

(note difference in number of chapters covered between profs-when in doubt, follow text using the detailed syllabus = "[topic #]" for guidance)

 

(I)                Molecular Design of Life

(1)                           [topic 1?] [alt 01] Prelude [text site]

(2)                           [topic 02] [alt 02] Protein Structure and Function [text site] (see "amino acids") [amino acid structure quiz]

(3)                           [topic 02] [alt 02] Exploring Proteins [text site]

(4)                           [topic 19] [alt 08] DNA and RNA: Molecules of Heredity [text site] [nucleic acid structure quiz]

(5)                           [topic 20] [alt 10] Flow of Genetic Information [text site]

(6)                           Exploring Genes [text site]

(II)             Proteins: Conformation, Dynamics, and Function

(7)                           [topic 03] [alt 03] Portrait of an Allosteric Protein [text site]

(8)                           [topic 05] [alt 04] Enzymes: Basic Concepts and Kinetics [text site]

(9)                           [topic 06] [alt 05] Catalytic Strategies [text site]

(10)                       [alt 06] Regulatory Strategies [text site]

(11)                       [topic 08] [alt 10] Membrane Structure and Dynamics [text site]

(12)                       Membrane Channels and Pumps [text site]

(13)                       Signal Transduction Cascades [text site]

(a)    (we will put this off until second half of course and then on an as-needed basis)

(14)                       Antibodies and T-Cell Receptors [text site]

(15)                       Molecular Motors [text site]

(16)                       Protein Folding and Design [text site]

(III)          Metabolic Energy: Generation and Storage

(17)                       [topic 07] [topic 09] [alt 11] Metabolism: Basic Concepts and Design [text site]

(18)                       [topic 10] [alt 07] Carbohydrates [text site] [carbohydrate structure quiz]

 

Should we have the midterm here?

 

(19)                       [topic 11] [alt 12] Glycolysis [text site] [week 6] [glycolysis structure & enzyme quiz]

(20)                       [topic 12] [alt 13] Citric Acid Cycle [text site] [week 6] [TCA cycle structure & enzyme quiz—week 7]

(21)                       [topic 13] [alt 14] Oxidative Phosphorylation [text site] [week 7]

(22)                       [topic 14] [alt 15] Pentose Phosphate Pathway and Gluconeogenesis (p. 569) [text site] [week 7]

(23)                       [topic 14] [topic 15]  [alt 16] Glycogen Metabolism [text site] [week 7]

(24)                       [topic 16] [alt 17] Fatty Acid Metabolism [text site] [week 8]

(25)                       [topic 17] [alt 18] Amino Acid Degradation and the Urea Cycle [text site] [week 8]

(26)                       [topic 18] Photosynthesis [text site] [week 8]

(IV)           Biosynthesis of Building Blocks

(27)                       Biosynthesis of Membrane Lipids and Steroids [text site]

(28)                       [alt 18] Biosynthesis of Amino Acids and Heme [text site]

(29)                       Biosynthesis of Nucleotides [text site]

(30)                       Integration of Metabolism [text site]

(V)              Genes: Replication and Expression

(31)                       [topic 19] DNA Structure, Replication, and Repair [text site] [week 9]

(32)                       Gene Rearrangements [text site] [week 9]

(33)                       RNA Synthesis and Splicing [text site] [week 9]

(34)                       [topic 21] Protein Synthesis [text site] [week 9]

(35)                       Protein Targeting [text site]

(36)                       [topic 22] Control of Gene Expression in Prokaryotes [text site] [week 10]

(37)                       Eukaryotic Chromosomes and Gene Express [text site]

 

The following constitute random jottings.

They do not necessarily constrain the amount material you are responsible for:

The Amino Acids

(from pages 20-23 of Stryer)

 

Name

[1],[2]

[3]

Structure[4]

Basic Properties

pK[5]

Glycine

G

Gly

-H

Hydrophobic[6]

 

Alanine

A

Ala

-CH3

Hydrophobic

 

Valine

V

Val

(see text)

Hydrophobic

 

Leucine

L

Leu

(see text)

Hydrophobic

 

Isoleucine

I

Ile

(see text)

Hydrophobic, two chiral carbons

 

Proline

P