- Incidence of metabolic changes among virus resistant mutants of a bacterial strain. Anderson, E.H. (1944). Proc. Natl. Acad. Sci. USA 30:397-403. Virus-resistant mutants have been isolated from a virus-sensitive strain of Escherichia coli utilizing the selective action of three strains of bacterial viruses active on the parent organism. the mutants differ from the original strain by their resistance to either one, any two, or all three viruses, in all possible combinations. Morphological studies and qualitative physiological tests show all strains tested to have characteristics similar to the original organism. Of the 57 mutants isolated in pure culture, 28 were unable to grow in a basal medium but were able to grow when 0.005 per cent yeast extract was added to this medium. Three representatives were systematically tested with various combinations of 8 vitamins, 23 amino acids, and hydrolyzed casein. None of these substances, added to the basal medium singly or in combination, would support the growth of the strains tested. [TOP OF PAGE]
- Bacteriophage therapy in bacillary dysentery. Boyd, J.S.K., Portnoy, B. (1944). Trans. R. Soc. Trop. Med. Hyg. 37:243-262. ["Some well controlled studies (on bacteriophage therapy), both experimental and clinical, produced results that were negative or where the observed effects were not regarded as useful." Quoted from Barrow & Soothill, 1997]. [TOP OF PAGE]
- Coordinate effects of electrolyte and antibody on the infectivity of bacteriophage. Hershey, A.D., Kalmanson, G.M., Bronfenbrenner, J.J. (1944). J. Immunol. 48:221-239. [TOP OF PAGE]
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