- Effect of electrolyte on the rate of inactivation of bacteriophage during precipitation. Bronfenbrenner, J.J. (1925). Proc. Soc. Exp. Biol. Med. 23:187-187. [TOP OF PAGE]
- Studies on the bacteriophage of d'Herelle. IV. Concerning the oneness of the bacteriophage. Bronfenbrenner, J.J., Korb, C. (1925). J. Exp. Med. 42:821-828. [TOP OF PAGE]
- On the nature of inactivation of the bacteriophage by alcohol. Bronfenbrenner, J.J., Korb, C. (1925). Proc. Soc. Exp. Biol. Med. 23:5-5. [TOP OF PAGE]
- On variants of B. pestis caviae resistant to lysis by bacteriophage. Bronfenbrenner, J.J., Korb, C. (1925). Proc. Soc. Exp. Biol. Med. 23:3-5. [TOP OF PAGE]
- Studies on the bacteriophage of d'Herelle. II. Effect of alcohol on the bacteriophage of d'Hérelle. Bronfenbrenner, J.J., Korb, C. (1925). J. Exp. Med. 42:419-429. [TOP OF PAGE]
- Studies on the bacteriophage of d'Hérelle. I. Is the lytic principle volatile? Bronfenbrenner, J.J., Kalmanson, G. (1925). J. Exp. Med. 41:73-79. [TOP OF PAGE]
- Studies on the bacteriophage of d'Herelle. III. Some of the factors determining the number and size of plaques of bacterial lysis on agar. Bronfenbrenner, J.J., Korb, C. (1925). J. Exp. Med. 42:483-497. The experiments reported above confirm the fact that lytic principle is distributed in active solution in a state of indivisible units. This permits its quantitative evaluation by serial dilution, as well as by plating on agar. The latter method, however, often gives readings considerably lower than those obtained by the broth dilution method of titration. By varying the concentration of agar it has been possible to show that the discrepency is due to adsorption of the lytic agent on agar. When the concentration of the latter is increased from 0.3 per cent to 2.5 per cent the number of plaques of lysis is reduced more than 100 times. At the same time the average size of the plaques also decreases approximately to one-tenth of the original.¶The size, as well as the number of plaques, has been found to depend also on the condition of the culture employed in titration. Thus, when the culture exposed to the action of lytic agent is composed of young susceptible bacteria, the greater the concentration of bacteria, the smaller the plaques.¶When the culture is composed partly of young and partly of old susceptible bacteria, both the size and the number of the plaques are diminished with the increase in the relative concentration of old bacteria. On the other hand, presence in the culture of resistant bacteria does not affect either the size or the number of the plaques so long as the relative concentration of susceptible bacteria in the culture is sufficient to allow formation of them. The plaques appearing in the presence of a high concentration of resistant variants in the culture are relatively indistinct owing to overgrowth.¶Under carefully controlled conditions the size of plaques is found to be determined by the character of the lytic filtrate. Thus in the case of lytic agents which act upon more than one bacterial species the size of the plaques remains constant, irrespective of the bacterial substratum used for the produciton of the active filtrate. [TOP OF PAGE]
- The transmissible lytic principle (bacteriophage) in relation to plant pathogens. Coons, G.H., Kotila, J.E. (1925). Phytopathology 15:357-370. [TOP OF PAGE]
- Essai de traitement de la peste bubonique par le bactériophage. d'Herelle, F. (1925). Presse Med. 33:1393-??? [TOP OF PAGE]
- Investigations on the blackleg disease of potato. Kotila, J.E., Coons, G.H. (1925). Michigan Agr. Exper. Sta. Tech. Bull. 67:[TOP OF PAGE]
- Über therapeutische Versuche mit bakteriophagem Lysin bei Kindern und Saüglingen. Munter, H., Boenheim, C. (1925). Zeitschr. F. Kinderheilk. 39:388-??? [TOP OF PAGE]
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